MSci MA (Cantab) PhD
Postdoctoral Research Associate at the Oxford Center for Integrative Systems Biology
Following my PhD in protein folding at Cambridge University I spent two years as a postdoctoral research associate at the University of Washington studying computational methods for protein folding. I returned to the UK to take up a position with Prof. Mark Sansom at the Department of Biochemistry in Oxford where I used computational methods to investigate the properties of membrane proteins. In 2008 I joined the Oxford Center for Integative Systems Biology in the group of Prof. Judy Armitage, working on the protein interactions controlling bacterial chemotaxis.
Biochemistry Lecturer, Christ Church. Biological Chemistry tutor, Department of Biochemistry. Tutorials on membrane proteins and bacterial signalling for various colleges.
Proteins play a role in all living things; they catalyse reactions that are vital for life, pass messages between cells and act as a scaffold maintaining cellular structure. I am interested in how proteins form the three-dimensional shape that is necessary for their function and how, once that shape has formed, proteins interact with each other and with their environment. During my research career I have gained experience in a variety of different experimental and computational methods that can be used to investigate protein structure and function. This has proven an invaluable background for my current position at the Oxford Centre for Integrative Systems Biology. The group in which I work uses a combination of biochemical and mathematical approaches to understand how bacteria move towards favourable environments. My project focuses on how changes in protein-protein interactions inside the cell lead to altered bacterial motion.
Scott K.A., Jefferys, E.E., Hall, B.A., Roberts, M.A.J., and Armitage, J.P. Bacterial Chemotaxis. In Bacterial Regulatory Networks.Horizon Press. In press
Scott, K.A., Porter, S.L., Bagg, E.A.L., Hamer, R., Hill, J.L., Wilkinson, D.A., and Armitage, J.P. Specificity of localization and phosphotransfer in the CheA proteins of Rhodobacter sphaeroides. (2010) Molecular Microbiology 76:318-330.
I am a member of the committee for the Cambridge Chemistry Challenge (www.C3L6.org). We aim to provide a challenging exam paper for UK year 12 students, in particular requiring the students to demonstrate problem-solving ability. I work with other members of the committee to write exam questions, teaching materials and online puzzles for our website.
Registered Charity Number: 1143423