Dr James Cantley

Lecturer in Medicine


BSc (Hons), MSc, DIC, PhD

Academic Background

I undertook my doctoral studies in the lab of Prof. Dominic Withers at University College London, where I investigated the molecular control of beta cell function by oxygen sensing and insulin signalling pathways. I received my PhD in 2007 and went on to a postdoctoral position at the Garvan Institute of Medical Research, Sydney, where I worked in the lab of Prof. Trevor Biden, and developed my interests in lipid signalling processes in the beta cell. Whilst in Australia I held two consecutive postdoctoral fellowships enabling me to develop my own research direction. I returned to the UK in 2013 to take up my current position as group leader within the Department of Physiology, Anatomy and Genetics at the University of Oxford. I currently hold the RD Lawrence Fellowship, funded by DiabetesUK.

Undergraduate Teaching

 Pre-clinical medicine.

Research Interests

My research interests revolve around the pancreatic beta cell: my group investigates the molecular mechanisms controlling insulin secretion, how beta cells adapt to metabolic demand during health and obesity, and how they fail during diabetes.


 A list of publications can be found on my Google Scholar page.


Open water swimming, triathlon, sailing.